The antioxidant advantage: CoQ10’s role in fighting gingivitis

CoQ₁₀ in dentistry: Practical applications

CoQ₁₀ it is found in several forms, including oral supplements, topical gels, and mouthwashes. Current CoQ₁₀ The gel can be applied directly to the gums, where it is absorbed into the tissues and offers local anti-inflammatory and antioxidant benefits. Studies have shown that applying CoQ₁₀ Gel in the periodontal pockets can help reduce gum inflammation, promote faster healing, and provide better results.^7,8

Using CoQ₁₀ with hyaluronic acid as a gel supplement was shown to be effective in the treatment of chronic periodontal disease in 2016.⁹ Dental professionals could even recommend CoQ10 supplementation as part of a comprehensive periodontal treatment plan, with clinical evidence showing that CoQ₁₀ supplementation at doses of 200 mg daily or higher for prolonged periods is safe, well tolerated, and results in a significant increase in plasma CoQ₁₀ flat. This dose also effectively reduces oxidative stress and reduces cardiovascular mortality.¹⁰

I am very optimistic about products that support the oral microbiome and enhance its health without disturbing its delicate balance. Consider making tonight’s dinner a piece of oily fish, with a spinach salad, nuts, seeds and avocado to boost your CoQ₁₀. Good appetite!

References

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2. Al-Hasso S. Coenzyme Q10: A review. Hospital Pharm. 2001? 36. (1): 51-66.

3. Rasoolzadeh EA, Shidfar F, Rasoolzadeh RA, Hezaveh ZS. The effect of coenzyme Q10 on periodontitis: a systematic review and meta-analysis of clinical trials. J Evid Based Dent Pract. 2022;22(2):101710. doi:10.1016/j.jebdp.2022.101710

4. Manthena S, Rao MV, Penubolu LP, Putcha M, Harsha AV. Effectiveness of oral CoQ10 supplementation as an adjunct to scaling and root planing in improving periodontal health. J Clin Diagn Res. 2015;9(8):ZC26-ZC28. doi:10.7860/JCDR/2015/13486.6291

5. Schmelzer C, Lindner I, Rimbach G, Niklowitz P, Menke T, Döring F. Functions of coenzyme Q10 in inflammation and gene expression. Bioagents. 2008? 32 (1-4): 179-183. doi:10.1002/biof.5520320121

6. Nakamura R, Littarru GP, Folkers K, et al. The effects of coenzyme Q10 on periodontal tissue regeneration. Proc Nat Acad Sci. 1974, 71(4):1456-1460. https://www.pnas.org/doi/pdf/10.1073/pnas.71.4.1456

7. Hanioka T, Tanaka M, Ojima M, Shizukuishi S, Folkers K. Effect of topical application of coenzyme Q10 on adult periodontitis. Mol Aspects Med. 1994, 15 Suppl:s241-s248. doi:10.1016/0098-2997(94)90034-5

8. Raut CP, Sethi KS, Kohale B, Mamajiwala A, Warang A. Subgingivally administered coenzyme Q10 in the treatment of chronic periodontitis among smokers: a randomized controlled clinical trial. J Oral Biol Craniofac Res. 2019? 9 (2): 204-208. doi:10.1016/j.jobcr.2018.05.005

9. Sharma V, Gupta R, Dahiya P, Kumar. Comparative evaluation of coenzyme Q 10-based gel and 0.8% hyaluronic acid gel in the treatment of chronic periodontitis. J Indian Soc Periodont. 2016? 20 (4): 374-380. doi:10.4103/0972-124X.183097

10. Rabanal-Ruiz Y, Llanos-González E, Alcain FJ. The use of coenzyme Q10 in cardiovascular diseases. Antioxidants (Basel). 2021? 10(5):755. doi: 10.3390/antiox10050755